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Frogs Can Be Frozen

And Come Back To Life

Certain species of frogs can freeze and then come back to life. This remarkable ability is known as cryo-preservation and is observed in species like the wood frog (Rana sylvatica), the spring peeper (Pseudacris crucifer), and the chorus frog (Pseudacris triseriata). Here's how it works: 


Freezing Process

During the winter, these frogs can survive being frozen solid. As temperatures drop, ice begins to form in their bodies, but only outside their cells. The frogs produce glucose or other cryoprotectants (substances that protect biological tissue from freezing damage) in their liver, which is released into their bloodstream. 


Cryoprotectants 

The high concentration of glucose acts as an antifreeze, lowering the freezing point of water inside the cells and preventing ice crystals from forming within the cells, which would otherwise cause cell damage. 


Controlled Ice Formation

Ice forms in the frogs' body cavity, bladder, and under their skin. Blood is withdrawn from extremities to concentrate glucose around vital organs. The heart stops beating, and the frog enters a state of suspended animation. 


Survival in a Frozen State

Frogs can remain in this frozen state for weeks or even months. Their metabolic processes slow down significantly, allowing them to survive without oxygen. 


Thawing and Revival

When temperatures rise in the spring, the frogs gradually thaw. Their heart starts beating again, and their organs resume normal function. Within a short period, they are able to return to their normal activities as if nothing happened.

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